Friday, September 03, 2010

Treatment options available for Kallmann syndrome or HH.

Hormone replacement only:

Tablets - not normally effective as dose is far too low

Daily gel application - gives good levels but can cause skin irritation with some
Daily patch application

Fortnightly or monthly injection, normally with Sustanon.

Injection every 3 months, such as Nebido. Not available in every country but appears to be very effective for treating KS or HH with stable levels throughout the treatment cycle.

Implants every 6 months, convienient but can leave scarring at implant site.

Injection with hCG / Pregnyl, can be expensive but the best method to give a more natural testosterone level and does have the advantage of increased testicular size in some men.

hCG is also the pre-cursor for fertility treatments. If a good response is achieved with hCG then a FSH type injection such as Gonal-F or Perganol is used to start sperm production and hopefully achieve fertility.

2 comments:

Anonymous said...

Hi. You describe a good response with hCG. What is that? I've been on hCG for a year now, and am waiting to start fsh in about 6 months, how do I know if its the right thing to do?

Neil Smith said...

Normally hCG or Pregnyl allows the testes to produce their own testosterone.

You might not notice any different in size but your testosterone levels should rise within weeks of starting hCG. Hopefully your testosterone levels have been checked since starting the hCG to check if the dose is correct and that the testes are now functional.

As long as the hCG is working the FSH when added should stimulate sperm production and an increase in testicular size within a couple of months of starting the injections.